The foreign policy of Iran and Russia has gone through different ups and downs, challenges, opportunities and events during different periods and has undergone different results in each period of time. But what is important in the foreign policy of the Islamic Republic of Iran after the victory of the Islamic Revolution is a policy that has placed Iran neither under Western domination nor an opportunity for the Russians to have a new hegemony in Iran. Iran's principled policy in relation to Russia and the West in the last four decades is to maintain the slogan of neither East nor West, which is also explicitly mentioned in the constitution, so the country's independence is the main priority of the foreign policy of the Islamic Republic of Iran. Iran must use Russia's authority to advance its security-military, economic and cultural goals in the region. Therefore, an independent Iran and a powerful Russia, which can maintain significant relations and maintain significant cooperation by maintaining their relations, cut off, most importantly, all Western and European countries that have no intention other than to profit and benefit from their interests. The present study seeks to answer the question that on what principles and foundations has the foreign policy of the Islamic Republic of Iran been based on the last four decades after the victory of the Islamic Revolution and what achievements and goals has it achieved? The findings of this study show the efforts of both countries to normalize relations and expand and maintain interests and promote Iran's position in the region according to the policies implemented in these decades and most importantly to map and advance the future at which the level of cooperation It has reached its maximum and both countries can have significant growth in the region in the face of sanctions and have no goal other than securing the region.